Novel therapies for pancreatic cancer: setbacks and progress
نویسندگان
چکیده
منابع مشابه
Targeted Therapies for Pancreatic Cancer
Pancreatic cancer is the third leading cause of cancer related death and by 2030, it will be second only to lung cancer. We have seen tremendous advances in therapies for lung cancer as well as other solid tumors using a molecular targeted approach but our progress in treating pancreatic cancer has been incremental with median overall survival remaining less than one year. There is an urgent ne...
متن کاملTargeted therapies for pancreatic cancer.
INTRODUCTION Pancreatic cancer is a devastating malignancy and a leading cause of cancer mortality. Furthermore, early diagnosis represents a serious hurdle for clinicians, as symptoms are non-specific and usually manifest in advanced, treatment-resistant stages of the disease. SOURCES OF DATA Here, we review the rationale and progress of targeted therapies currently under investigation. AR...
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Targeted therapies for cancer can be broadly defined as treatments directed against abnormally activated molecules or physiological processes required for maintenance or progression of tumours. In recent years, many targeted therapies have become established in daily clinical practice and a huge number of agents are in various stages of pre-clinical and clinical development. The concept of targ...
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With regard to resectable disease, two recent phase III randomized trials showed that postoperative chemotherapy, either 5fluorouracil or gemcitabine, significantly prolongs overall and disease-free survival with respect to observation alone [1, 2]. A Radiation Therapy Oncology Group (RTOG) phase III randomized trial showed significantly better survival after gemcitabine chemotherapy with respe...
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The financial crisis of 1997-1998 in East and Southeast Asia has raised questions about the sustainability of some hitherto admired modes of poverty reduction. But this paper argues that there remain important lessons to learn from Asia’s great ascent out of poverty since the Second World War. It remains important that well before the setback struck, much of this area had eliminated food povert...
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ژورنال
عنوان ژورنال: Future Oncology
سال: 2010
ISSN: 1479-6694,1744-8301
DOI: 10.2217/fon.10.70